Study of Some Modern (Von Willbrand Factors and Copeptin) and Routine (Troponin I and hs-CRP) Biochemical Markers in Patients with Ischemic Heart Diseases in Karbala Province
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Ischemic heart diseases (IHD), Von willbrand factors (VWF), High-sensitivity C-reactive protein (hs-CRP).
Abstract
Present study was diagnosed at Cardiologist, Imam AL-Hassan Al-Mujtaba Teaching Hospital and Karbala center for heart diseases and surgery in Imam Al-Hussein Teaching Hospital from March to August 2024.comfort might result from this decreased blood flow. High blood pressure, high cholesterol, smoking, diabetes, obesity, and a sedentary lifestyle are the primary risk factors. This study's goal is to assess and contrast a few biochemical markers in Karbala province people who have ischaemic heart disease and those who do not. This study was designed as a cross-sectional study. 100 individuals were involved, divided into Two main group with age range 25-85 years as Group 1 without Ischemic Heart Diseases divided into two subgroups (Without risk factors and With risk factors (Hypertension, diabetes mellitus, obesity ,smoking ),Group 2 with Ischemic Heart Diseases divided into three subgroups(Stable angina ,Unstable angina and Myocardial infraction). All the patients included in the current study were diagnosed by Cardiologist in Imam Al-Hassan Al-Mujtaba Teaching Hospital, and Karbala Center for Heart Diseases and Surgery in Imam Al-Hussein Teaching Hospital from March 2024 to August 2024. In the present study, copeptin in patients was measured regularly and other biochemical factors include VWF, hsCRP, and Troponin I were also analyzed and the results of these biochemical signatures have been analyzed by employing enzyme-linked immunosorbent assay (ELIAS). The result of current study showed that the concentration of troponin I is higher in myocardial infraction group than other groups ( without risk factors, with risk factors, stable angina, unstable angina) and the concentration of hs-CRP is higher without risk factors, stable angina, unstable angina and especially in myocardial infraction This result implies that copeptien is higher in unstable angina and in myocardial infraction continuing tordial infraction.
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