Navigating Multi-Drug Resistant Tuberculosis: A Case Report on Treatment Challenges in a Non-Smoking Male

Insharah khan (1) , Mohd Farhan Shehzad (2) , Hannan Husain (3) , Abhijith Murali (4) , Mohd Alam (5) , Smriti Tiwari (6)
(1) Department of Pharmacy Practice, Teerthanker Mahaveer College of Pharmacy, Teerthanker Mahaveer University, Moradabad (U. P.), India-244001. , India
(2) Department of Pharmacy Practice, Teerthanker Mahaveer College of Pharmacy, Teerthanker Mahaveer University, Moradabad (U. P.), India-244001. , India
(3) Department of Pharmacy Practice, Teerthanker Mahaveer College of Pharmacy, Teerthanker Mahaveer University, Moradabad (U. P.), India-244001. , India
(4) Department of Pharmacy Practice, Teerthanker Mahaveer College of Pharmacy, Teerthanker Mahaveer University, Moradabad (U. P.), India-244001 , India
(5) Department of Pharmacy Practice, Teerthanker Mahaveer College of Pharmacy, Teerthanker Mahaveer University, Moradabad (U. P.), India-244001. , India
(6) Department of Pharmacy Practice, Teerthanker Mahaveer College of Pharmacy, Teerthanker Mahaveer University, Moradabad (U. P.), India-244001. , India

Abstract

A 39-year-old non-smoker man came in with persistent cough, fever, and significant weight loss over the past 5 months. Having previously been treated for pulmonary tuberculosis, he showed signs of malnutrition and lung crackles upon examination. Sputum tests confirmed active multi-drug resistant tuberculosis (MDR-TB), resistant to isoniazid, rifampicin, ethambutol, and streptomycin. Laboratory results indicated anemia and elevated liver enzymes. Chest imaging revealed cavitary lesions and opacities in the lungs. He was initiated on second-line anti-TB drugs with directly observed therapy. Regular follow-ups were scheduled to monitor his progress, highlighting the complexities of managing MDR-TB and the critical importance of treatment adherence.


 

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Authors

Insharah khan
Mohd Farhan Shehzad
Hannan Husain
Abhijith Murali
Mohd Alam
Smriti Tiwari
khan, I., Shehzad, M. F., Husain, H., Murali, A., Alam, M., & Tiwari, S. (2024). Navigating Multi-Drug Resistant Tuberculosis: A Case Report on Treatment Challenges in a Non-Smoking Male. Journal of Current Medical Research and Opinion, 7(06), 2700–2705. https://doi.org/10.52845/CMRO/2024/7-6-1
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