A Study on the Association Between CYP19 Exon 3 Variants and the Hormone Estrogen in Local Female Goats
Abstract
The goal of this study was to determine how the genetic polymorphism of the CYP19 gene exon 3 affected the levels of the estrogen hormone in female goats.In Babil Governorate/AlQaism district, Blood samples from female goats were collected from their fields. To measure the estrogen levels, the Enzyme Linked Immuno Sorbent Assay was utilized (ELISA). The CYP19 gene's third axon, measuring 140 bp in length, was removed, and the genotypes of this axon were identified in accordance with the different nucleotide sequences and their correlation with
the levels of the estrogen hormone in the samples. In samples of local female goats, the genotype distributions of the CYP19 gene were analyzed by percentages. 40 %, 26.66 %, and 33.34 %, for TG, GG and TT genotypes respectively. We conclude that the TG genotype is superior to CYP19 gene 3 exon in domestic goats from Iraq. This outperformed the pure genotypes TT and GG because its estrogen hormone content was much higher (P≤ 0.01). These findings made it abundantly evident to us that girls with to ensure that a chosen generation possesses desirable qualities, we advise choosing genotype TG moms for their offspring.
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