A Comprehensive Review of Burkholderia sp.
Article Sidebar
Abstract
This comprehensive review gives a systematic overview of the genus Burkholderia by its taxonomy, drug resistance, various aspects of pathogenicity in humans and animals as well as diagnostics methods and phylogeny. Initially, Pseudomonas cepacia was discovered to include Burkholderia but now this genus contains a lot of species and each new one has different roles, such as strict ecological niche ecology, plant symbiosis, and pathogenicity towards plants, animals and humans. Progress of molecular biology area has dramatically improved the discrimination and diagnosis of the Burkholderia that established its genetic diversity and quite intricate responses to the host(s). The description here explores the disease transmission ways of Burkillerdiaceraillea species, that have serious clinical consequences meaning for the humans and animals including B. cepacia complexa, B. pseudomallei, and B. mallei species. There will be the emergence of antimicrobial resistance in the trans-Burkholderia reservoirs which require extensive efforts over time through the research that will provide an ideal therapeutic approach. In addition to this analysis, the chapter discusses purely evolutionary relationships inside Burkholderia generes. With this in mind, we can detect accurate species identification of the genus to investigate the epidemiology, develop targeted treatments and prevent outbreaks.
Full text article
References
Aung, N. M., Su, K. K., Chantratita, N., & Tribuddharat, C. (2023). Workflow for identification of Burkholderia pseudomallei clinical isolates in Myanmar. Japanese Journal of Infectious Diseases, 76(2), 106-112.
Bach, E., Sant'Anna, F. H., dos Santos Seger, G. D., & Passaglia, L. M. P. (2022). Pangenome inventory of Burkholderia sensu lato, Burkholderia sensu stricto, and the Burkholderia cepacia complex reveals the uniqueness of Burkholderia catarinensis. Genomics, 114(1), 398-408.
Bach, E., Volpiano, C. G., Sant’Anna, F. H., & Passaglia, L. M. P. (2023). Genome-based taxonomy of Burkholderia sensu lato: Distinguishing closely related species. Genetics and Molecular Biology, 46, e20230122.
Baker, S. M., Settles, E. W., Davitt, C., Gellings, P., Kikendall, N., Hoffmann, J., ... & Morici, L. A. (2021). Burkholderia pseudomallei OMVs derived from infection mimicking conditions elicit similar protection to a live-attenuated vaccine. npj Vaccines, 6(1), 18.
Beca, F. A., Sengillo, J. D., Robles-Holmes, H. K., Iyer, P. G., Miller, D., Yannuzzi, N. A., & Flynn, H. W. (2023). Endophthalmitis caused by Burkholderia cepacia complex (BCC): clinical characteristics, antibiotic susceptibilities, and treatment outcomes. Journal of Ophthalmic Inflammation and Infection, 13(1), 48.
Behroozian, S., Zlosnik, J. E. A., Xu, W., Li, L. Y., & Davies, J. E. (2023). Antibacterial Activity of a Natural Clay Mineral against Burkholderia cepacia Complex and Other Bacterial Pathogens Isolated from People with Cystic …. Microorganisms.
Bellés-Sancho, P., Beukes, C., James, E. K., & Pessi, G. (2023). Nitrogen-Fixing Symbiotic Paraburkholderia Species: Current Knowledge and Future Perspectives. Nitrogen.
Burtnick, M. N., Dance, D. A., Vongsouvath, M., Newton, P. N., Dittrich, S., Sendouangphachanh, A., ... & Brett, P. J. (2024). Identification of Burkholderia cepacia strains that express a Burkholderia pseudomallei-like capsular polysaccharide. Microbiology Spectrum, e03321-23.
Bzdyl, N. (2021). Characterisation of Cyclophilin Proteins from Burkholderia Pseudomallei and Their Role in Pathogenesis.
Bzdyl, N. M., Moran, C. L., Bendo, J., & Sarkar-Tyson, M. (2022). Pathogenicity and virulence of Burkholderia pseudomallei. Virulence.
Chang, C. Y., & Lee, H. L. (2023). A fatal case of persistent Burkholderia pseudomallei bacteraemia with severe pneumonia and splenic abscess. Journal of Ayub Medical College Abbottabad, 35(2).
Choh, L. C., Ong, G. H., Chua, E. G., Vellasamy, K. M., Mariappan, V., Khan, A. M., ... & Vadivelu, J. (2021). Absence of BapA type III effector protein affects Burkholderia pseudomallei intracellular lifecycle in human host cells. Process Biochemistry, 108, 48-59.
Choi, O., Kim, S., Kang, B., Lee, Y., Bae, J., & Kim, J. (2021). Genetic Diversity and Distribution of Korean Isolates of Burkholderia glumae. Plant Disease.
De Volder, A. L., Teves, S., Isasmendi, A., Pinheiro, J. L., Ibarra, L., Breglia, N., ... & Degrossi, J. (2021). Distribution of Burkholderia cepacia complex species isolated from industrial processes and contaminated products in Argentina. International Microbiology, 24, 157-167.
Depoorter, E., De Canck, E., Peeters, C., Wieme, A. D., Zlosnik, J. E., LiPuma, J. J., ... & Vandamme, P. (2020). Burkholderia cepacia complex taxon K: where to split?. Frontiers in microbiology, 11, 559949.
Desoutter, A., Deshayes, T., Vorimore, F., Klotoe, B., Durand, B., Colot, J., ... & Laroucau, K. (2024). Isolation of Burkholderia pseudomallei from a goat in New Caledonia: implications for animal and human health monitoring and serological tool comparison. BMC Veterinary Research, 20(1), 114.
Duong, H. T. (2022). Rapid culture independent nucleic acid diagnostics methodologies for the specific detection of the Burkholderia cepacia complex–addressing a microbiological.
Elery, Z. K. (2023). Investigation of Key Mechanisms of Contact Dependent Growth Inhibition Systems in Burkholderia cepacia Complex Species.
Elshafie, H. S. & Camele, I. (2021). An Overview of Metabolic Activity, Beneficial and Pathogenic Aspects of Burkholderia Spp.. Metabolites.
Espinosa-Victoria, D., López-Reyes, L., Carcaño-Montiel, M. G., & Serret-López, M. (2020). The Burkholderia genus: between mutualism and pathogenicity. Revista mexicana de fitopatología, 38(3), 337-359.
Fu, H., Gan, L., Tian, Z., Han, J., Du, B., Xue, G., ... & Yuan, J. (2022). Rapid detection of Burkholderia cepacia complex carrying the 16S rRNA gene in clinical specimens by recombinase-aided amplification. Frontiers in Cellular and Infection Microbiology, 12, 984140.
Ghazali, A. K., Firdaus-Raih, M., Uthaya Kumar, A., Lee, W. K., Hoh, C. C., & Nathan, S. (2023). Transitioning from soil to host: comparative transcriptome analysis reveals the Burkholderia pseudomallei response to different niches. Microbiology spectrum, 11(2), e03835-22.
Green, H. R. (2022). The Development of Diagnostic Immunoassays for Melioidosis and Ebola Virus Disease.
Grund, M. E., Choi Soo, J., Cote, C. K., Berisio, R., & Lukomski, S. (2021). Thinking Outside the Bug: Targeting Outer Membrane Proteins for Burkholderia Vaccines. Cells.
Gutiérrez Santana, J. C. & Coria Jiménez, V. R. (2024). Burkholderia cepacia complex in cystic fibrosis: critical gaps in diagnosis and therapy. Annals of Medicine.
Häfliger, E., Atkinson, A., & Marschall, J. (2020). Systematic review of healthcare-associated Burkholderia cepacia complex outbreaks: presentation, causes and outbreak control. Infection prevention in practice.
Hamidizade, M., Taghavi, S. M., Soleimani, A., Bouazar, M., Abachi, H., Portier, P., & Osdaghi, E. (2024). Wild mushrooms as potential reservoirs of plant pathogenic bacteria: a case study on Burkholderia gladioli. Microbiology Spectrum, e03395-23.
He, G., Zeng, Y., He, Q., Liu, T., Li, N., Lin, H., ... & Yao, W. (2023). A case report of Burkholderia mallei infection leading to pneumonia. Combinatorial Chemistry & High Throughput Screening, 26(1), 241-245.
Hrenovic, J., Seruga Music, M., Drmic, M., Pesorda, L., & Bedenic, B. (2022). Characterization of Burkholderia cepacia complex from environment influenced by human waste. International journal of environmental health research, 32(9), 2112-2122.
Janesomboon, S., Muangsombut, V., Srinon, V., Meethai, C., Tharinjaroen, C. S., Amornchai, P., ... & Korbsrisate, S. (2021). Detection and differentiation of Burkholderia species with pathogenic potential in environmental soil samples. Plos one, 16(1), e0245175.
Jayasinghearachchi, H. S., Muthugama, T. A., Masakorala, J., Kulasekara, U. S., Jayaratne, K., Jayatunga, D. D. N., ... & Corea, E. M. (2023). Burkholderia pseudomallei in soil and natural water bodies in rural Sri Lanka: A hidden threat to public health. Frontiers in Veterinary Science, 9, 1045088.
Jia, J. & Lu, S. E. (2024). Comparative Genome Analyses Provide Insight into the Antimicrobial Activity of Endophytic Burkholderia. Microorganisms.
Jin, Y., Zhou, J., Zhou, J., Hu, M., Zhang, Q., Kong, N., ... & Yue, J. (2020). Genome-based classification of Burkholderia cepacia complex provides new insight into its taxonomic status. Biology Direct, 15, 1-14.
Kavanaugh, L. G., Harrison, S. K., Flanagan, J. N., & Steck, T. R. (2021). Antibiotic cycling reverts extensive drug resistance in Burkholderia multivorans. Antimicrobial Agents and Chemotherapy, 65(8), 10-1128.
Khan, M. A. S., Miah, M. I., & Rahman, S. R. (2022). Subtractive proteomic analysis for identification of potential drug targets and vaccine candidates against Burkholderia pseudomallei K96243. Informatics in Medicine Unlocked.
Kwayess, R., Al Hariri, H. E., Hindy, J. R., Youssef, N., Haddad, S. F., & Kanj, S. S. (2022). Burkholderia cepacia infections at sites other than the respiratory tract: A large case series from a tertiary referral hospital in Lebanon. Journal of Epidemiology and Global Health, 12(3), 274-280.
LaBonte, M. L. (2022). Diagnostic uncertainty, microbes, and the isolation of people with cystic fibrosis. Journal of the History of Medicine and Allied Sciences, 77(2), 186-216.
Lee, H. H., Park, J., Jung, H., & Seo, Y. S. (2021). Pan-Genome Analysis Reveals Host-Specific Functional Divergences in Burkholderia gladioli. Microorganisms.
Loaiza, C. D., Duhan, N., Lister, M., & Kaundal, R. (2021). In silico prediction of host–pathogen protein interactions in melioidosis pathogen Burkholderia pseudomallei and human reveals novel virulence factors and their targets. Briefings in Bioinformatics, 22(3), bbz162.
Loeven, N. (2022). Role of the Burkholderia cenocepacia Effector TecA in Pathogenesis During Lung Infection.
Lood, C., Peeters, C., Lamy-Besnier, Q., Wagemans, J., De Vos, D., Proesmans, M., ... & Vandamme, P. (2021). Genomics of an endemic cystic fibrosis Burkholderia multivorans strain reveals low within-patient evolution but high between-patient diversity. PLoS Pathogens, 17(3), e1009418.
Lord, R., Jones, A. M., & Horsley, A. (2020). Antibiotic treatment for Burkholderia cepacia complex in people with cystic fibrosis experiencing a pulmonary exacerbation. Cochrane Database of Systematic Reviews, (4).
Luk, K. S., Tsang, Y. M., Ho, A. Y. M., To, W. K., Wong, B. K. H., Wong, M. M. L., & Wong, Y. C. (2022). Invasive Burkholderia cepacia complex infections among persons who inject drugs, Hong Kong, China, 2016–2019. Emerging Infectious Diseases, 28(2), 323.
Maki Al-Nasrawy, L., Abdali, S. A., & Mohammed Jawad, S. (2022). Molecular Research Comparing the Probabilities of Burkholderia Cepacia Bacterium Diagnosis Procedures. Archives of Razi Institute, 77(2), 717-725.
Merritt, A. J. & Inglis, T. J. J. (2024). Burkholderia pseudomallei and Burkholderia mallei. Molecular Medical Microbiology.
Meumann, E. M., Limmathurotsakul, D., Dunachie, S. J., Wiersinga, W. J., & Currie, B. J. (2024). Burkholderia pseudomallei and melioidosis. Nature Reviews Microbiology, 22(3), 155-169.
Mohanty, L., Dhal, S., Mohanty, D. P., Sahoo, R. K., & Mishra, D. N. (2023). Phenotypic Characterization of Burkholderia Spp: In a Tertiary care hospital of Eastern India.
Morales-Ruíz, L. M., Rodríguez-Cisneros, M., Kerber-Díaz, J. C., Rojas-Rojas, F. U., Ibarra, J. A., & Estrada-de Los Santos, P. (2022). Burkholderia orbicola sp. nov., a novel species within the Burkholderia cepacia complex. Archives of Microbiology, 204(3), 178.
Morya, R., Salvachúa, D., & Thakur, I. S. (2020). Burkholderia: an untapped but promising bacterial genus for the conversion of aromatic compounds. Trends in Biotechnology.
Mullins, A. J. & Mahenthiralingam, E. (2021). The hidden genomic diversity, specialized metabolite capacity, and revised taxonomy of Burkholderia sensu lato. Frontiers in microbiology.
Narayanan, S. (2022). Burkholderia mallei and Burkholderia pseudomallei. Veterinary Microbiology.
Nasiri, M., Zarrin, A., RoshankarRudsari, S., & Khodadadi, J. (2023). Glanders (Burkholderia mallei infection) in an Iranian man: A case report. IDCases.
Okomo, U., Senghore, M., Darboe, S., Bojang, E., Zaman, S. M., Hossain, M. J., ... & Kampmann, B. (2020). Investigation of sequential outbreaks of Burkholderia cepacia and multidrug-resistant extended spectrum β-lactamase producing Klebsiella species in a West African tertiary hospital neonatal unit: a retrospective genomic analysis. The Lancet Microbe, 1(3), e119-e129.
Orababa, O. Q., Adesida, S. A., Peters, R. F., AbdulGanniyu, Z., Olakojo, O., & Abioye, A. (2023). Showing the limitations of available phenotypic assays to detect Burkholderia pseudomallei from clinical specimens in Nigeria. Access Microbiology, 5(10), 000604-v5.
Pal, G., Saxena, S., Kumar, K., Verma, A., Sahu, P. K., Pandey, A., ... & Verma, S. K. (2022). Endophytic Burkholderia: Multifunctional roles in plant growth promotion and stress tolerance. Microbiological Research, 265, 127201.
Parfitt, K. (2022). Using next generation sequencing approaches to define the population biology of the neglected cystic fibrosis lung pathogen Burkholderia multivorans.
Porter, L. A., & Goldberg, J. B. (2011). Influence of neutrophil defects on Burkholderia cepacia complex pathogenesis. Frontiers in cellular and infection microbiology, 1, 9.
Pratama, A. A., Jiménez, D. J., Chen, Q., Bunk, B., Spröer, C., Overmann, J., & van Elsas, J. D. (2020). Delineation of a subgroup of the genus Paraburkholderia, including P. terrae DSM 17804T, P. hospita DSM 17164T, and four soil-isolated fungiphiles, reveals remarkable genomic and ecological features—proposal for the definition of a P. hospita species cluster. Genome biology and evolution, 12(4), 325-344.
Prommachote, W., Mala, W., Songsri, J., Khoosuilee, J., Wansu, S., Srisara, J., ... & Klangbud, W. K. (2022). Diversity of Colony Morphotypes, Biochemical Characteristics, and Drug Susceptibility Patterns of Burkholderia pseudomallei Isolated from Humans, Animals, and Environmental Sources in Thailand. Trends in Sciences, 19(8), 153-153.
Purushotham, P., Mohanty, S., Chappity, P., Mishra, T. S., & Mahapatra, A. (2021). Identification and characterization of Burkholderia pseudomallei from localized pyogenic infections in Eastern India: a clinico-microbiological study. The American journal of tropical medicine and hygiene, 104(4), 1252.
Romero-Gutiérrez, K. J., Dourado, M. N., Garrido, L. M., Olchanheski, L. R., Mano, E. T., Dini-Andreote, F., ... & Araújo, W. L. (2020). Phenotypic traits of Burkholderia spp. associated with ecological adaptation and plant-host interaction. Microbiological research, 236, 126451.
Santos Júnior, E. L. D., Moura, J. D. C. R., Protásio, B. K. P. F., Parente, V. A. S., & Veiga, M. H. N. D. (2020). Clinical repercussions of Glanders (Burkholderia mallei infection) in a Brazilian child: a case report. Revista da Sociedade Brasileira de Medicina Tropical, 53, e20200054.
Shanmugasundaram, K., Singha, H., Saini, S., & Tripathi, B. N. (2022). 16S rDNA and ITS Sequence Diversity of Burkholderia mallei Isolated from Glanders-Affected Horses and Mules in India (2013–2019). Current microbiology, 79(1), 31.
Suvanasuthi, R., Cheewasatheinchaiyaporn, T., Wat-Aksorn, K., & Promptmas, C. (2023). Nucleic Acid Amplification Free-QCM-DNA Biosensor for Burkholderia pseudomallei Detection. Current Microbiology, 80(12), 376.
Syed, I. (2022). Identification and Characterization of a Burkholderia pseudomallei Factor H-Binding Protein.
Taitt, C. R., Leski, T. A., Compton, J. R., Chen, A., Berk, K. L., Dorsey, R. W., ... & Vora, G. J. (2024). Impact of template denaturation prior to whole genome amplification on gene detection in high GC-content species, Burkholderia mallei and B. pseudomallei. BMC Research Notes, 17(1), 1-8.
Tavares, M., Kozak, M., Balola, A., & Sá-Correia, I. (2020). Burkholderia cepacia complex bacteria: a feared contamination risk in water-based pharmaceutical products. Clinical microbiology reviews, 33(3), 10-1128.
Topluoglu, S., Taylan-Ozkan, A., & Alp, E. (2023). Impact of wars and natural disasters on emerging and re-emerging infectious diseases. Frontiers in Public Health.
Tsuji, M. & Kadota, I. (2020). Identification and phylogenetic analysis of Burkholderia cepacia complex bacteria isolated from rot of onion bulbs in Tohoku region of Japan. Journal of General Plant Pathology.
Vandamme, P., & Dawyndt, P. (2011). Classification and identification of the Burkholderia cepacia complex: Past, present and future. Systematic and applied microbiology, 34(2), 87–95.
Wang, G., Glaser, L., Scott, N. E., Fathy Mohamed, Y., Ingram, R., Laroucau, K., & Valvano, M. A. (2021). A glycoengineered antigen exploiting a conserved protein O-glycosylation pathway in the Burkholderia genus for detection of glanders infections. Virulence, 12(1), 493-506.