Prednisolone Induced Exogenous Cushing Syndrome: A Case Report

Subhankar  Das; Jatin  Kaushik; Anushka Sharad  Dube; Pooja  Biswas; Faiqua  Jamal; Silky  Kumari

doi:10.52845/CMRO/2023/6-10-2

Subhankar Das ⁽¹⁾ , Jatin Kaushik ⁽²⁾ , Anushka Sharad Dube ⁽³⁾ , Pooja Biswas ⁽⁴⁾ , Faiqua Jamal ⁽⁵⁾ , Silky Kumari ⁽⁶⁾

(1) Department of Doctor of Pharmacy, Institute for Medical Sciences and Research Centre, Jaipur National University, Jaipur, 302017, Rajasthan, India. , India

(2) Department of Doctor of Pharmacy, Institute for Medical Sciences and Research Centre, Jaipur National University, Jaipur, 302017, Rajasthan, India , India

(3) Department of Doctor of Pharmacy, Institute for Medical Sciences and Research Centre, Jaipur National University, Jaipur, 302017, Rajasthan, India. , India

(4) Department of Doctor of Pharmacy, Institute for Medical Sciences and Research Centre, Jaipur National University, Jaipur, 302017, Rajasthan, India. , India

(5) Department of Doctor of Pharmacy, Institute for Medical Sciences and Research Centre, Jaipur National University, Jaipur, 302017, Rajasthan, India. , India

(6) Department of Doctor of Pharmacy, Institute for Medical Sciences and Research Centre, Jaipur National University, Jaipur, 302017, Rajasthan, India. , India

https://doi.org/10.52845/CMRO/2023/6-10-2

Issue
Vol. 6 No. 10 (2023)

Keywords:

Cushing syndrome, cortisol, corticosteroids, prednisolone

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Abstract

Exogenous Cushing syndrome (ECF) develops when a patient uses synthetic (man-made) glucocorticoids to treat a condition. These drugs have cortisol-like effects on the body. ECS may be caused by oral corticosteroids such as cortisone or prednisone. In an adult, CS can appear as proximal muscular weakness, facial plethora, wasting of the extremities along with higher fat in the abdominal region and face, wide reddish striae, bruising without evident trauma, and supraclavicular fat deposits. In this case report, a 39-year-old woman was suspected of having Cushing syndrome because of his clinical symptoms and low cortisol levels due to taking oral corticosteroids for the last 2 years. She presented weakness, joint pain, buffalo hump, skin infection, diabetes mellitus type-2, along with suspicion of Central hypothyroidism. MRI scan of the brain showed demyelinating lesions. After a physical examination and laboratory data confirmed that the patient was diagnosed with corticosteroid-induced exogenous Cushing syndrome.

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