Impact of medications for opioid use disorder on healthcare resource utilization and costs for patients served by a state Medicaid program An exploratory retrospective matched-cohort analysis of South Carolina Medicaid claims data

Dr. Orsolya Lunacsek (1) , Maher Abdel-Sattar (2) , Ms. Augustina Ogbonnaya (3) , Mr. William Mullen (4) , Dr. Ann Wheeler (5) , Dr. Christian Heidbreder (6) , Dr. Bryan Amick (7)
(1) * At the time of this research, Dr. Lunacsek was an employee of Xcenda. , United States
(2) a:1:{s:5:"en_US";s:6:"Author";} , United States
(3) Xcenda, Carrollton, TX, USA , United States
(4) Indivior, Chesterfield, VA, USA , United States
(5) Indivior, Chesterfield, VA, USA , United States
(6) Indivior, Chesterfield, VA, USA , United States
(7) South Carolina Department of Health and Human Services, Columbia, SC, USA , United States

Abstract

Objectives: Although evidence-based recommendations from treatment guidelines support the use of medications for opioid use disorder (MOUD) in addition to psychosocial counseling, about 86.6% of patients diagnosed with opioid use disorder (OUD) do not receive MOUD and several barriers still restrict access to MOUD in the United States. This study assesses the impact of MOUD on healthcare resource utilization (HCRU) and costs for Medicaid beneficiaries.


Methods: An exploratory retrospective matched-cohort analysis was performed among Medicaid patients not concurrently enrolled in Medicare using anonymized claims data from South Carolina Medicaid between 7/1/2016 and 12/31/2019. Patients newly diagnosed with OUD who received MOUD were matched based on age, gender, and race to patients who did not receive MOUD to evaluate HCRU and costs in the 6 months prior to and 12 months following initial OUD diagnosis.


Results: A total of 397 matched pairs of MOUD and non-MOUD patients were identified for this analysis. A significantly lower percentage of patients had emergency department visits (63.2% vs 74.3%; P=0.0005) and hospitalizations (21.9% vs 37.8%; P<0.0001) in the matched MOUD cohort compared to the non-MOUD cohort. All-cause total direct costs were numerically lower for the matched MOUD cohort ($15,212 vs $17,451; P=0.3388), as numerically higher all-cause pharmacy costs associated with MOUD utilization were offset by significantly lower all-cause medical costs compared to the non-MOUD cohort ($9,265 vs $14,819; P=0.0005).


Conclusions: The results of this analysis suggest that MOUD utilization has a positive association with reducing HCRU and all-cause medical costs for Medicaid patients with OUD.

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Authors

Dr. Orsolya Lunacsek
Maher Abdel-Sattar
maher.abdel-sattar@xcenda.com (Primary Contact)
Ms. Augustina Ogbonnaya
Mr. William Mullen
Dr. Ann Wheeler
Dr. Christian Heidbreder
Dr. Bryan Amick
Lunacsek, O. ., Abdel-Sattar, M., Ogbonnaya, A., Mullen, W., Wheeler, A., Heidbreder, C., & Amick, B. (2022). Impact of medications for opioid use disorder on healthcare resource utilization and costs for patients served by a state Medicaid program: An exploratory retrospective matched-cohort analysis of South Carolina Medicaid claims data. Journal of Current Medical Research and Opinion, 5(10), 1426–1438. https://doi.org/10.52845/CMRO/2022/5-10-2
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