Specific Chemotherapy Treatments for Patients with Ovarian Endodermal Sinus Tumors

Abstract

Ovarian endodermal sinus tumors are a neoplasm of germinal origin derived from the primordial cells that during their migration from the caudal area to the gonadal region undergo mutations that progress to become malignant cells that proliferate constantly. Appearance is unilateral; it is considered the germinal tumor with the highest malignancy rate. (20%) Early diagnosis could increase patient survival. An exploratory investigation included the five last years in the pubmed, science, and Cochrane was carried out to evaluate the evidence of the diagnosis and / or treatment of these tumors. It was found that mortality is due to delayed diagnosis and ineffective treatment. It is necessary to determine the chemotherapy treatments that effectively attack this type of neoplastic cells, which behave differently from other types of tumors.