Analysis of Fermentation Product of Bioactive Compounds of Escherichia coli Isolated from UTI and Evaluation Effect of Four Tradition Medicinal Plant as Antimicrobial Activity

Rabab J.H. Al Hasseny (1) , Abbas K. Al-Mansoori (2) , Ahmed Obaid Hossain (3)
(1) Medical Microbiology, Department of Health Food and Nutrition, College of Food Science, Al-Qasim Green University, Iraq. , Iraq
(2) Department of Genetic Engineering, College of Biotechnology, Al-Qasim Green University, Iraq. , Iraq
(3) Department of Medical Biotechnology, College of Biotechnology, Al-Qasim Green University, Iraq. , Iraq

Abstract

The purpose of this study was to examine four plant extracts for their antibacterial activity against Escherichia coli in vitro and to examine the bioactive chemical products of this bacteria.


Method: Gas chromatography-mass spectrometry (GC-MS) methods were used to investigate the bioactive chemical components, also called secondary metabolites. Afterwards, the antibacterial activity of the Escherichia coli methanolic extract was evaluated in a laboratory setting.


Results: The following were found in the Escherichia coli GC-MS analysis:   The compounds listed include 1,2-Epithio-3-hexanol, Oxa-4-azacyclohexane, 1-DL-Lysine monohydrochloride, 2-Methoxy-5-methylpyridine, 5-Methylquinoline, Methyl oleate hydroperoxide, methyl octadeca-9,12,15-trienoate, N-benzylhexadecanamide, Dimethylacetamide, 2-amino-N-ethyl-N-methylacetamide, methyl (Z)-18-hydroperoxyoctadec-9-enoate, Methyl hexadecanoate, n-Butyl oleate, Methyl 16-methylheptadecanoate, 2-Amino-N-methylacetamide. Urtica dioica  (Crude) (26.09±0.21) was very highly active against Escherichia coli

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Authors

Rabab J.H. Al Hasseny
Abbas K. Al-Mansoori
Ahmed Obaid Hossain
Hasseny , R. J. A. ., Al-Mansoori , A. K. ., & Hossain , A. O. . (2024). Analysis of Fermentation Product of Bioactive Compounds of Escherichia coli Isolated from UTI and Evaluation Effect of Four Tradition Medicinal Plant as Antimicrobial Activity. Journal of Current Medical Research and Opinion, 7(02), 2127–2134. https://doi.org/10.52845/CMRO/2024/7-2-10

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