Challenges in decreasing incidence of positive margins in breast-conserving surgery for breast cancer
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Abstract
Breast cancer remains the most common cancer worldwide. 1 in 9 women is diagnosed in their lifetime with an increasing trend. Surgery has been the mainstay of treatment for breast cancer, accompanied by chemotherapy, radiotherapy, hormone therapy, and biological therapies. Evolution away from a radical approach toward breast-conserving procedures brought in major advantages for the patient's benefit providing overall equivalence in outcomes. One of the most important conditions for such outcomes while preserving the breast in early breast cancer is represented by surgery with negative margins. In 2014 The Society of Surgical Oncology (SSO) and the American Society for Therapeutic Radiology and Oncology (ASTRO) established guidelines for breast-conserving surgery margins for early breast cancer, followed by 2016 guidelines for margins on carcinoma in situ. These guidelines were internationally adopted and have a strong impact on clinical practice. We present our experience and challenges in decreasing the incidence of positive margins in lumpectomies for invasive and in situ carcinomas.
This is an observational study with a comparison to new data consensus while recognizing the challenges in decreasing the incidence of positive margins in our breast-conserving surgeries.
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